NPPB antibody (AA 13-27)

Catalog No. ABIN317049

The Mouse Monoclonal anti-NPPB antibody (Clone 18H5) (ABIN317049) specifically detects NPPB in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for NPPB antibody (AA 13-27) (ABIN317049)

Target: NPPB (Natriuretic Peptides B (NPPB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NPPB antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 18H5

Product Details anti-NPPB Antibody

Binding Specificity: AA 13-27

Specificity: This antibody detects the amino-terminal fragment of pro-brain natriuretic peptide (amino acids 13-20), also known as NT-proBNP, a cleavage product during the proteolytic activation of BNP.

Characteristics: Synonyms: NPPB, Brain natriuretic peptide, BNP, proBNP, Gamma-brain natriuretic peptide

Purification: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Amino acids 13-27 of NT-proBNP

Isotype: IgG1

Application Details

Application Notes: ELISA. Western Blotting: Detects a band of approximately 9 kDa when using recombinantNT-proBNP. Immunoassay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing. Should this product contain a precipitate werecommend microcentrifugation before use.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for NPPB

Target: NPPB (Natriuretic Peptides B (NPPB))

Alternative Name: Natriuretic Peptides B

Background: NT-proBNP is a secreted protein which is a member of the natriuretic peptide family, which is predominantly secreted from the cardiac ventricles in response to volume and pressure overload. NT-proBNP is more stable than BNP in serum, and has become a useful biomarker of heart failure.Synonyms: BNP, Brain natriuretic peptide, Gamma-brain natriuretic peptide, NPPB, proBNP

Gene ID: 4879

UniProt: P16860

Pathways: Hormone Activity