HSP90AA1 antibody (AA 289-300)

Catalog No. ABIN318867

The Rabbit Polyclonal anti-HSP90AA1 antibody (ABIN318867) specifically detects HSP90AA1 in WB and EIA. The antibody is reactive with Human, Mouse, Rat, Monkey, Chicken and Drosophila melanogaster samples.

Quick Overview for HSP90AA1 antibody (AA 289-300) (ABIN318867)

Target: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Reactivity: Human, Mouse, Rat, Monkey, Chicken, Drosophila melanogaster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP90AA1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HSP90AA1 Antibody

Binding Specificity: AA 289-300

Specificity: This antibody detects heat shock protein 90 alpha (HSP90a).

Purification: Purified

Immunogen: Synthetic peptide corresponding to amino acids 289-300 of human heat shock protein 90 alpha.

Isotype: IgG

Application Details

Application Notes: ELISA: 1: 5000 - 1: 25000. Western Blot: 1: 500 - 1: 2500, detects a band of approximately 90 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.2 containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.

Target Details for HSP90AA1

Target: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Alternative Name: HSP90AA1 / HSP90 alpha

Background: HSP90a is one of two HSP90 isoforms together with HSP90b. These isoforms are encoded by different genes and under normal conditions assist the folding of newly synthesised proteins, and are also important in cellular processes such as hormone signalling and cell cycle control. In response to mutation or environmental stress, HSP90 expression is upregulated as part of the heat shock response, and function to maintain newly destabilised proteins in a folding competent state. HSP90 can also affect the epigenetic state at specific loci, leading to phenotype modulation. Induction of HSP90a by c-Myc may control the activity of multiple signal pathways involved in cellular transformation.Synonyms: HSP86, HSP90A, HSPC1, HSPCA, Heat shock 86 kDa, Heat shock protein HSP 90-alpha, NY-REN-38

Gene ID: 9606

UniProt: P07900

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals