CTNNB1 antibody (Tyr654)
Quick Overview for CTNNB1 antibody (Tyr654) (ABIN319394)
Target
See all CTNNB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Tyr654
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Specificity
- This antibody detects endogenous levels of total beta-catenin protein.
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Purification
- Immunoaffinity Chromatography.
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Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human beta-Catenin around the phosphorylation site of Tyrosine 654 (A-T-YP-A-A).
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Application Notes
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Western Blot (1/500-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at-20 °C.
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- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
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Alternative Name
- Catenin beta-1
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Background
- Synonyms: Beta-catenin, CTNNB, CTNNB1
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Gene ID
- 1499
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NCBI Accession
- NP_001091679
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UniProt
- P35222
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Pathways
- WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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