FCGR1A antibody

Catalog No. ABIN319804

This Mouse Monoclonal antibody specifically detects FCGR1A in FACS and Func. It exhibits reactivity toward Human and Monkey.

Quick Overview for FCGR1A antibody (ABIN319804)

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCGR1A antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 10-01-14

Product Details anti-FCGR1A Antibody

Specificity: This antibody recognises the human CD64 cell surface antigen. This antibody blocks binding of immunoglobulin to FcRI.

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Endotoxin Level: Low Endotoxin

Immunogen: Human monocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0-Ag14 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: Use 10 μL of 1/50-1/200 diluted antibody to label 10^6 cells in 100 μL. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: < 0.01 Eu/Ug

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing no preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Target Details for FCGR1A

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Alternative Name: CD64 / FCGR1A

Background: CD64 is a 75kD molecule expressed by monocytes, interferon gamma stimulated granulocytes, myelomonocytic leukaemias and myeloid cell lines.Synonyms: Fc-gamma RI, Fc-gamma RIA, FcRI, FcgammaRIa, High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I

Gene ID: 2209

NCBI Accession: NP_000557

UniProt: P12314

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process