»
Antibodies
»
anti-Crystallin, alpha A (CRYAA) antibody
Crystallin, alpha A (CRYAA) antibody
| Antigen |
|
| Synonyms |
CRYA1, HSPB4, Crya1, lop18, Acry-1, Crya-1, DAcry-1, AI323437, cryaa-A, CRYAA, fc06h04, MGC92036, zgc:92036, wu:fc06h04, alpha-a-crystallin |
| Clonality |
Monoclonal (C9F2) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
|
| Catalog no. |
ABIN320356 |
| Quantity |
50 µl (1.0 mg/ml) (Variants) |
| Price |
265.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Alternative name
|
Alpha-crystallin A chain
|
|
Swiss-Prot
|
P02489
|
|
Immunogen
|
Recombinant human a -Crystallin A protein
|
|
Cross-Reactivity
|
Human, Rat (Rattus)
|
|
Isotype
|
IgG1 (Matching secondary antibodies)
|
|
Clone
|
C9F2
|
|
Description
|
A -crystallins, a major protein of the ocular lens, are thought to play a role in maintaining lens transparency, which are composed of two gene products a -A and a -B, for acidic and basic, respectively. a -crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP). They act as molecular chaperones and hold unfolded or misfolded proteins in large, water-soluble low molecular weight aggregates. These heterogeneous aggregates consist of 30-40 subunits of a -crystallins, and the a -A and a -B subunits have a 3:1 ratio, respectively. Two additional functions of a -crystallins are an autokinase activity and the participation in the intracellular architecture. Alternate Names: Alpha-crystallin A chain, Heat shock protein beta-4, HSPB4, CRYA1, Heat shock protein beta 4, Alpha-A crystallin, Zonular Central Nuclear Cataract, Crystallin Alpha 1.
|
|
Specificity
|
The antibody recognizes human and rat a -Crystallin A. Other species not tested.
|
|
Application Notes
|
ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution 1:1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Concentration
|
1.0 mg/ml
|
|
Purification
|
Purified
|
|
Buffer
|
PBS containing 0.09% sodium azide
|
|
Storage
|
Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
|
|
Research Area
|
Neurology, Enzymes
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Crystallin, alpha A (CRYAA)", type "Antibodies"