Fibroblast Growth Factor Receptor 2 (FGFR2) antibody

Antigen: Fibroblast Growth Factor Receptor 2 (FGFR2)

Synonyms: Fgfr2, BEK, JWS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM, FLJ98662, Bek, svs, Fgfr7, Fgfr-2, Fgfr-7, KGFRTr, AU043015, AW556123, MGC102519, wu:fc56c05, FGFR2, cek3, FGF-R, FGFR2IIIb, fgfr72IIIb, FGFR, bek, jws, cfd1, ect1, kgfr, tk14, tk25, bfr-1, cd332, k-sam, xfgfr2, DKFZp469H1521

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN334399

Additional Information

Alternative name: FGFR2

Gene ID: 2263, 14183 (mouse), 25022 (rat)

Immunogen: C-GREKEITASPDY

Description: All names and symbols: FGFR2 , fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome), BEK , BFR-1 , CD332 , CEK3 , CFD1 , ECT1 , JWS , K-SAM , . Official Symbol: FGFR2 . RefSeq number(s): NP_000132.1, NP_075259.2

Specificity: This antibody is expected to recognise both reported isoforms (NP_000132.1, NP_075259.2). Human, Mouse, Rat

Synonyms: Fgfr2, BEK, JWS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM, FLJ98662, Bek, svs, Fgfr7, Fgfr-2, Fgfr-7, KGFRTr, AU043015, AW556123, MGC102519, wu:fc56c05, FGFR2, cek3, FGF-R, FGFR2IIIb, fgfr72IIIb, FGFR, bek, jws, cfd1, ect1, kgfr, tk14, tk25, bfr-1, cd332, k-sam, xfgfr2, DKFZp469H1521

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx 100kDa band observed in Human lysates of cell line A549 (calculated MW of 92.0kDa according to NP_000132.1 and of 92.1kDa according to NP_075259.2). Recommended concentration: 0.3-1µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Growth Factors, Lineage Markers, Tyrosine Kinases, Angiogenesis, Receptors

Restrictions: For Research Use only

Images

ABIN334399 (0.3µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Easton, Pooley, Dunning et al.: "Genome-wide association study identifies novel breast cancer susceptibility loci." in: Nature, Vol. 447, Issue 7148, pp. 1087-93, 2007 (PubMed).

McGrath, Lee, Buring et al.: "Novel breast cancer risk alleles and endometrial cancer risk." in: International journal of cancer. Journal international du cancer, Vol. 123, Issue 12, pp. 2961-4, 2008 (PubMed).