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Patched 1 (PTCH1) antibody

Antigen

Patched 1 (PTCH1)
Synonyms PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11, FLJ26746, FLJ42602, ptc-1, ptch1, Ptch, Ptch2, ptc1, XPtc1, patched, patched1, PTCH1
Clonality Polyclonal
Host
Reactivity
Alternatives

Zebrafish (Danio rerio)
Application
Alternatives ELISA, Immunofluorescence (IF)
2 references available
Catalog no. ABIN334456
Quantity 100µg  (100µg specific antibody in 200µl)
Price 423.80 $   Plus shipping costs $35.00
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Additional Information
Application Details Publications Alternatives Secondary Antibodies back to top

Alternative name Patched 1
Immunogen Peptide with sequence C-QTGSKKEPFNYSQ, from the internal region of the protein sequence according to NP_571063.1
Description All names and symbols: ptc1, patched 1 , ptc-1, etID309849.2, patched1. Official Symbol: ptc1. RefSeq number(s): NP_571063.1.
Specificity Expected from sequence similarity: Zebrafish

Application Details
Publications Alternatives Secondary Antibodies back to top

Application Notes Peptide ELISA: antibody detection limit dilution 1:32000. This product has been successfully used in immunofluorescence studies of zebrafish tumors (Ju et al, Mol Cancer. 2009 Jun 25,8:40., PMID: 19555497). Recommended concentration: 1-3µg/ml.
Concentration 100µg specific antibody in 200µl
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Restrictions For Research Use only

Publications
Application Details Alternatives Secondary Antibodies back to top

Publications Laforest, Brown, Poleo et al.: "Involvement of the sonic hedgehog, patched 1 and bmp2 genes in patterning of the zebrafish dermal fin rays." in: Development (Cambridge, England), Vol. 125, Issue 21, pp. 4175-84, 1998 (PubMed).

Ju, Spitsbergen, Eden et al.: "Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish." in: Molecular cancer, Vol. 8, pp. 40, 2009 (PubMed).