CD45 antibody (C-Term)
Quick Overview for CD45 antibody (C-Term) (ABIN337379)
Target
See all CD45 (PTPRC) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purification
- Purified
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Immunogen
- Peptide derived from C-terminal sequence of human CD45.
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Application Notes
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Approved: IHC, IHC-P (10 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 20 mM Tris-HCl, pH 8.0, 20 mg/mL BSA, 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Aliquot to Avoid freeze/thaw cycles.
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
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Alternative Name
- CD45
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Background
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Name/Gene ID: PTPRC
Subfamily: R1/R6
Family: Protein Phosphatase
Synonyms: PTPRC, B220, CD45R, CD45, gp180, Leukocyte common antigen, L-CA, Leucocyte common antigen, LY5, T200, T200 glycoprotein, T200 leukocyte common antigen, CD45 antigen, LCA -
Gene ID
- 5788
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UniProt
- P08575
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
Target
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