SPRY4 antibody (N-Term)

Catalog No. ABIN347129

The Rabbit Polyclonal anti-SPRY4 antibody is suitable to detect SPRY4 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for SPRY4 antibody (N-Term) (ABIN347129)

Target: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRY4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SPRY4 Antibody

Binding Specificity: N-Term

Specificity: Reacts with human 32 kDa Spry-4 protein

Cross-Reactivity: Mouse (Murine), Cow (Bovine), Chicken

Cross-Reactivity (Details): Cross reacts with mouse, bovine and chicken. Not tested on other species.

Purification: Antiserum

Immunogen: Synthetic peptide derived from N terminal region of Sprouty homolog 4 (Spry-4)

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/100 to 1/500 - WB : 1/500 to 1/2 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for SPRY4

Target: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Alternative Name: SPRY4

Background: Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.

UniProt: Q9C004