Meteorin, Glial Cell Differentiation Regulator (METRN) (Internal Region) antibody
| Antigen | Meteorin, Glial Cell Differentiation Regulator (METRN) |
| Synonyms | MGC2601, C16orf23, c380A1.2, Hyrac, 1810034B16Rik, RGD1306222, mtrn, zgc:92132, wu:fb81a08, METRN |
| Binding Site |
 Alternatives Internal Region |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity | |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Immunohistochemistry (IHC), Western Blotting (WB) |
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3 references available |
| Catalog no. | ABIN350461 |
| Quantity | 500 µg |
| Price | 454.67 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 7 to 8 Business Days |
Additional Information
| Alternative name | Meteorin (METRN) |
| UniProt | Q9UJH8 |
| Immunogen | A synthetic peptide from the internal region of human Meteorin (METRN) conjugated to an immunogenic carrier protein was used as the immunogen. |
| Format | Lyophilized |
| Isotype | IgG |
| Description | Function: Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Subcellular location: Secreted Also known as: Meteorin, METRN. |
| Specificity | Appears to be specific for Meteorin. |
Application Details
| Application Notes | IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. |
| Purity | IgG |
| Purification | The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Storage | Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Restrictions | For Research Use only |
Publications
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Daniels, Peden, Lloyd et al.: "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16." in: Human molecular genetics, Vol. 10, Issue 4, pp. 339-52, 2001 (PubMed).
Nishino, Yamashita, Hashiguchi et al.: "Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension." in: The EMBO journal, Vol. 23, Issue 9, pp. 1998-2008, 2004 (PubMed). Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed). |
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Alternatives
Alternatives for antigen "Meteorin, Glial Cell Differentiation Regulator (METRN)", type "Antibodies"
| Hosts | Rabbit (21), Rat (2), Goat (1) |
| Reactivities | Mouse (Murine) (22), Human (21), Rat (Rattus) (18) |
| Applications | Immunofluorescence (IF) (15), Western Blotting (WB) (9), ELISA (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1) |
| Conjugates | Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1) |
| Epitopes | Internal Region (2), N-Term (1) |
