Meteorin, Glial Cell Differentiation Regulator (METRN) (Internal Region) antibody

Details for Product No. ABIN350461
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Antigen
Synonyms C16orf23, c380A1.2, Hyrac, 1810034B16Rik, RGD1306222, mtrn, zgc:92132, wu:fb81a08, METRN
Epitope
Internal Region
(2), (2), (1)
Reactivity
Human
(20), (19), (12), (12)
Host
Rabbit
(19), (4), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(14), (13), (10), (7), (6), (4), (2)
Pubmed 3 references available
Catalog no. ABIN350461
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the internal region of human Meteorin (METRN) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity Specific for P2RX7.
Purification The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
IgG
Alternative Name Meteorin (METRN)
Background Function: Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia.
Subcellular location: Secreted Also known as: Meteorin, METRN.
UniProt Q9Z1M0
Research Area Neurology
Application Notes A concentration of 10-50 µg/mL is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
General Daniels, Peden, Lloyd et al.: "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16." in: Human molecular genetics, Vol. 10, Issue 4, pp. 339-52, 2001 (PubMed).

Nishino, Yamashita, Hashiguchi et al.: "Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension." in: The EMBO journal, Vol. 23, Issue 9, pp. 1998-2008, 2004 (PubMed).

Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16...." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).

Hosts (19), (4), (1), (1)
Reactivities (20), (19), (12), (12)
Applications (14), (13), (10), (7), (6), (4), (2)
Conjugates (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (1)
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