Vacuolar Protein Sorting 35 Homolog (S. Cerevisiae) (vps35) (N-Term) antibody

Details for Product No. ABIN350530
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms VPS35, 23.m05999, DKFZp459E1510, CG5625, DVps35, Dmel\\CG5625, Dvps35, dvps35, vps35, MGC81959, bZ34G2.3, si:rp71-34g2.3, wu:fa66e03, wu:fb95c08, zgc:136268, AI647796, Mem3, MEM3, PARK17
Epitope
N-Term
(7), (3), (2), (2), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(17), (5), (4), (3)
Host
Rabbit
(8), (7), (2)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(17), (8), (8), (5), (4), (3), (2), (2)
Pubmed 5 references available
Quantity 500 μg
Options
Shipping to United States (Change)
Availability Will be delivered in 7 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN350530
454.67 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide from the n-terminal human Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35, VPS35, MEM3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, mouse.
Isotype IgG
Specificity Specific for VPS35.
Alternative Name VPS35
Background Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
Subcellular location: Cytoplasm. Membrane, Peripheral membrane protein.
Tissue specificity: Ubiquitous. Highly expressed in heart, brain, placenta, skeletal muscle, spleen, thymus, testis, ovary, small intestine, kidney and colon. Also known as: Vesicle protein sorting 35, Maternal-embryonic 3, VPS35, MEM3.
Research Area Signaling
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Edgar, Polak: "Human homologues of yeast vacuolar protein sorting 29 and 35." in: Biochemical and biophysical research communications, Vol. 277, Issue 3, pp. 622-30, 2000 (PubMed).

Haft, de la Luz Sierra, Bafford et al.: "Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4105-16, 2000 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Vergues, Luton, Gruber et al.: "The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor." in: Nature cell biology, Vol. 6, Issue 8, pp. 763-9, 2004 (PubMed).

Hierro, Rojas, Rojas et al.: "Functional architecture of the retromer cargo-recognition complex." in: Nature, Vol. 449, Issue 7165, pp. 1063-7, 2007 (PubMed).

Validation Images
Did you look for something else?
back to top