Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) (Cytoplasmic Domain) antibody

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Antigen
  • P2X3
  • P2RX3
  • 4930513E20Rik
  • purinergic receptor P2X, ligand-gated ion channel, 3
  • P2RX3
  • P2rx3
Epitope
Cytoplasmic Domain
19
15
14
8
3
2
1
1
1
1
Reactivity
Human
58
38
30
3
2
1
Host
Rabbit
63
3
3
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
49
22
18
17
13
7
7
5
5
1
1
Options
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Immunogen A synthetic peptide from the cytoplasmic domain of human P2X3 (P2RX3, P2X purinoceptor 3, ATP receptor) conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 85% identity with rat and mouse sequence.
Isotype IgG
Specificity Specific for P2RX3.
Alternative Name P2RX3 (P2RX3 Antibody Abstract)
Background Function: Receptor for ATP that acts as a ligand gated ion channel.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: P2RX3, P2X purinoceptor 3, ATP receptor, Purinergic receptor.
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Garcia-Guzman, Soto, Gomez-Hernandez, Lund, Stuehmer: "Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue." in: Molecular pharmacology, Vol. 51, Issue 1, pp. 109-18, 1997 (PubMed).