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RAB5 antibody (Internal Region)

This Sheep Polyclonal antibody specifically detects RAB5 in WB and IHC. It exhibits reactivity toward Mouse.
Catalog No. ABIN350782

Quick Overview for RAB5 antibody (Internal Region) (ABIN350782)

Target

See all RAB5 (RAB5A) Antibodies
RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Reactivity

  • 96
  • 61
  • 42
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 7
  • 7
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Mouse

Host

  • 100
  • 11
  • 3
  • 1
Sheep

Clonality

  • 91
  • 24
Polyclonal

Conjugate

  • 58
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RAB5 antibody is un-conjugated

Application

  • 85
  • 41
  • 36
  • 30
  • 30
  • 14
  • 14
  • 14
  • 13
  • 13
  • 5
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Binding Specificity

    • 18
    • 15
    • 11
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    Purpose

    Sheep antibody to RAB5A

    Specificity

    Specific for RAB5A.

    Cross-Reactivity

    Mouse, Rat

    Cross-Reactivity (Details)

    Other species not yet tested.

    Purification

    IgG

    Immunogen

    A synthetic peptide from the internal region of mouse Ras-related protein Rab-5A (RAB5A) conjugated to blue carrier protein has been used as the antigen. The antigen is homologous in rat.

    Isotype

    IgG
  • Application Notes

    IHC WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

    Handling Advice

    Avoid freeze and thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    Expiry Date

    12 months
  • Target

    RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

    Alternative Name

    RAB5A

    Background

    FUNCTION: Required for the fusion of plasma membranes and early endosomes. ENZYME REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the SUBCELLULAR LOCATION: Cell membrane, Lipid-anchor, Cytoplasmic side. Early endosome membrane, Lipid-anchor. Melanosome.

    UniProt

    Q9CQD1

    Pathways

    Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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