RAB5 antibody (Internal Region)
Quick Overview for RAB5 antibody (Internal Region) (ABIN350782)
Target
See all RAB5 (RAB5A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Purpose
- Sheep antibody to RAB5A
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Specificity
- Specific for RAB5A.
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Cross-Reactivity
- Mouse, Rat
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Cross-Reactivity (Details)
- Other species not yet tested.
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Purification
- IgG
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Immunogen
- A synthetic peptide from the internal region of mouse Ras-related protein Rab-5A (RAB5A) conjugated to blue carrier protein has been used as the antigen. The antigen is homologous in rat.
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Isotype
- IgG
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Application Notes
- IHC WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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Handling Advice
- Avoid freeze and thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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Expiry Date
- 12 months
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- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
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Alternative Name
- RAB5A
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Background
- FUNCTION: Required for the fusion of plasma membranes and early endosomes. ENZYME REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the SUBCELLULAR LOCATION: Cell membrane, Lipid-anchor, Cytoplasmic side. Early endosome membrane, Lipid-anchor. Melanosome.
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UniProt
- Q9CQD1
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Pathways
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
Target
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