PRDM14 antibody (PR Domain Containing 14) (N-Term)

Details for Product anti-PRDM14 Antibody No. ABIN356723, Supplier: Log in to see
Antigen
  • PRDM14
  • prmd14
  • fc16b12
  • wu:fc16b12
  • PFM11
  • PR domain containing 14
  • Prdm14
  • PRDM14
  • prdm14
  • LOC100347807
Epitope
N-Term
17
16
12
10
3
2
2
2
2
1
1
1
1
Reactivity
Human
71
20
13
7
6
5
3
2
2
1
Host
Rabbit
44
23
6
3
Clonality
Polyclonal
Conjugate
This PRDM14 antibody is un-conjugated
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
58
48
33
23
13
8
7
4
3
2
1
1
Options
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PRDM14.
Isotype Ig
Specificity This antibody is specific to PRDM14 (PFM11) (N-term).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name PRDM14 / PFM11 (PRDM14 Antibody Abstract)
Background Similar to acetylation and phosphorylation, histone methylation at the N terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET domain family, and another 17 make up the PR domain family that is related to the SET domain family. PRDM14 is part of a family of PR domain genes that are involved in tumorigenesis. It may function as a transcription factor.Synonyms: PR domain zinc finger protein 14, PR domain-containing protein 14
Gene ID 63978, 9606
UniProt Q9GZV8
Application Notes ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-PRDM14 antibody (PR Domain Containing 14) (N-Term) (ABIN356723) anti-PR Domain Containing 14 (PRDM14) (N-Term) antibody
 image for anti-PRDM14 antibody (PR Domain Containing 14) (N-Term) (ABIN356723) anti-PR Domain Containing 14 (PRDM14) (N-Term) antibody (Image 2)
Background publications Xiao, Wilson, Gamblin: "SET domains and histone methylation." in: Current opinion in structural biology, Vol. 13, Issue 6, pp. 699-705, 2003 (PubMed).

Dias Neto, Correa, Verjovski-Almeida, Briones, Nagai, da Silva, Zago, Bordin, Costa, Goldman, Carvalho, Matsukuma, Baia, Simpson, Brunstein, de Oliveira, Bucher, Jongeneel, OHare, Soares, Brentani et al.: "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 7, pp. 3491-6, 2000 (PubMed).

Jiang, Huang: "The yin-yang of PR-domain family genes in tumorigenesis." in: Histology and histopathology, Vol. 15, Issue 1, pp. 109-17, 2000 (PubMed).