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TLR7 antibody (N-Term)

TLR7 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357057
  • Target See all TLR7 Antibodies
    TLR7 (Toll-Like Receptor 7 (TLR7))
    Binding Specificity
    • 16
    • 14
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 105
    • 51
    • 26
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 96
    • 16
    Rabbit
    Clonality
    • 87
    • 25
    Polyclonal
    Conjugate
    • 49
    • 13
    • 10
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR7 antibody is un-conjugated
    Application
    • 80
    • 49
    • 29
    • 16
    • 13
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects TLR7 at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human and Mouse.
    Purification
    Protein Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human TLR7.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TLR7 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    TLR7 (Toll-Like Receptor 7 (TLR7))
    Alternative Name
    TLR7 (TLR7 Products)
    Synonyms
    TLR7-like antibody, RGD1563357 antibody, toll like receptor 7 antibody, toll-like receptor 7 antibody, TLR7 antibody, Tlr7 antibody
    Background
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.Synonyms: Toll-like receptor 7
    Molecular Weight
    120921 Da
    Gene ID
    51284, 9606
    UniProt
    Q9NYK1
    Pathways
    TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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