Desmin antibody
Quick Overview for Desmin antibody (ABIN357901)
Target
See all Desmin (DES) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody detects Desmin. Predicted to cross react with Mouse (100 % Antigen Homology).
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Purification
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T16 of human Desmin.
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Isotype
- Ig Fraction
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Application Notes
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ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Desmin (DES)
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Alternative Name
- Desmin
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Background
- Desmin is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in the gene encoding desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Synonyms: DES
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Molecular Weight
- 53536 Da
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Gene ID
- 1674, 9606
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UniProt
- P17661
Target
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