SLAMF1 antibody (pTyr281)

Catalog No. ABIN358469

The Rabbit Polyclonal anti-SLAMF1 antibody is suitable to detect SLAMF1 in samples from Human. It has been validated for EIA.

Quick Overview for SLAMF1 antibody (pTyr281) (ABIN358469)

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAMF1 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-SLAMF1 Antibody

Binding Specificity: pTyr281

Specificity: This antibody detects SLAMF1/CD150 pTyr281.

Purification: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y281 of human SLAMF1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SLAMF1

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Alternative Name: CD150 / SLAMF1

Background: SLAMF1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam

Molecular Weight: 37231 Da

Gene ID: 6504, 9606

UniProt: Q13291