SLC29A1 antibody (pSer254)

Catalog No. ABIN358541

There is 1 publication for this product available. The Rabbit Polyclonal anti-SLC29A1 antibody is suitable to detect SLC29A1 in samples from Human. It has been validated for EIA.

Quick Overview for SLC29A1 antibody (pSer254) (ABIN358541)

Target: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC29A1 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-SLC29A1 Antibody

Binding Specificity: pSer254

Specificity: This antibody reacts to ENT1 (SLC29A1) pSer254.

Purification: Protein A column, followed by two-step phosphospecific peptide affinity purification

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S254 of human ENT1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-SLC29A1 antibody (ABIN358541)

Dephoure, Zhou, Villén, Beausoleil, Bakalarski, Elledge, Gygi: "A quantitative atlas of mitotic phosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 31, pp. 10762-7, (2008) (PubMed).

Target Details for SLC29A1

Target: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Alternative Name: SLC29A1 / ENT1

Background: ENT1 is a member of the equilibrative nucleoside transporter family. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.Synonyms: Equilibrative nucleoside transporter 1, Solute carrier family 29 member 1

Gene ID: 2030, 9606

UniProt: Q99808

Pathways: Carbohydrate Homeostasis, Synaptic Membrane