MAGED1 antibody (Middle Region)

Catalog No. ABIN358657

This Rabbit Polyclonal antibody specifically detects MAGED1 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for MAGED1 antibody (Middle Region) (ABIN358657)

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGED1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-MAGED1 Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to MAGED1.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MAGED1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Alternative Name: MAGE-D1

Background: MAGED1 is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway.Synonyms: MAGE tumor antigen CCF, MAGED1, Melanoma-associated antigen D1, NRAGE, Neurotrophin receptor-interacting MAGE homolog

Gene ID: 9500

NCBI Accession: NP_001005332

UniProt: Q9Y5V3

Pathways: Neurotrophin Signaling Pathway