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PRKCB (Isoform beta 1,Isoform beta 2,C-Term) antibody

Antigen

PRKCB
Epitope
Alternatives

Isoform beta 1,Isoform beta 2,C-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Catalog no. ABIN359059
Quantity 0.1 mg  (0.25 mg/ml)
Price 285.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies back to top

Characteristics Synonyms: PKC-beta, PKC beta, PKC-B, PKCB, PRKCB1, Protein kinase C beta type
Gene ID 5579
Swiss-Prot P05771
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the C-terminal region of human PKC.
Cross-Reactivity Human
Isotype Ig  (Matching secondary antibodies)
Description Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that canbe activated by calcium and second messenger diacylglycerol. PKC family membersphosphorylate a wide variety of protein targets and are known to be involved in diversecellular signaling pathways. PKC family members also serve as major receptors for phorbolesters, a class of tumor promoters. Each member of the PKC family has a specificexpression profile and is believed to play a distinct role in cells. PKC beta is one of the PKCfamily members. This protein kinase has been reported to be involved in many differentcellular functions, such as B cell activation, apoptosis induction, endothelial cellproliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinasemay also regulate neuronal functions and correlate fear-induced conflict behavior afterstress. Alternatively spliced transcript variants encoding distinct isoforms have beenreported. Isoform 1 uses an alternate exon at the 3' end compared to isoform 2, whichincludes a part of the coding region. The resulting isoform 1 has a distinct and shorterC-terminus, as compared to isoform 2.
Specificity This antibody reacts to PKC beta 1/2. Species: Human. Others not tested.

Application Details
Alternatives Secondary Antibodies back to top

Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.25 mg/ml
Purification Purified
Buffer PBS with 0.09% (W/V) sodium azide
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Restrictions For Research Use only