STK38 antibody (C-Term)

Catalog No. ABIN359159

Product Details anti-STK38 Antibody

Target: STK38 (serine/threonine Kinase 38 (STK38))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK38 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to STK38.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human STK38.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/250 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for STK38

Target: STK38 (serine/threonine Kinase 38 (STK38))

Alternative Name: STK38 (STK38 Products)

Synonyms: NDR antibody, NDR1 antibody, 5830476G13Rik antibody, 9530097A09Rik antibody, AA617404 antibody, Ndr1 antibody, trc antibody, si:ch1073-272h17.2 antibody, wu:fj80h03 antibody, zgc:55572 antibody, serine/threonine kinase 38 antibody, serine/threonine kinase 38 S homeolog antibody, serine/threonine kinase 38b antibody, serine/threonine kinase 38a antibody, STK38 antibody, Stk38 antibody, stk38.S antibody, stk38b antibody, stk38a antibody

Background: Stk38,also known as NUCLEAR DBF2-RELATED PROTEIN, contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.Synonyms: NDR1, Nuclear Dbf2-related kinase 1, Serine/threonine-protein kinase 38

Gene ID: 11329, 9606

UniProt: Q15208