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MAPK4 antibody (Mitogen-Activated Protein Kinase 4) (N-Term)

Details for Product anti-MAPK4 Antibody No. ABIN359555, Supplier: Login to see
Antigen
  • ERK-4
  • ERK3
  • Erk4
  • MAPK 4
  • PRKM4
  • p63MAPK
  • A330097D03Rik
  • Erk3
  • Prkm4
  • p63Mapk
  • erk4
  • wu:fi27d11
  • zgc:55498
  • ATMPK4
  • F2N1.1
  • F2N1_1
  • MAP kinase 4
Alternatives
anti-Human MAPK4 antibody for ELISA
Epitope
N-Term
23
22
15
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
67
16
4
1
1
1
1
Host
Rabbit
62
8
2
2
1
Clonality
Polyclonal
Conjugate
This MAPK4 antibody is un-conjugated
4
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
65
40
36
12
12
4
2
1
1
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NAPK4.
Isotype Ig
Specificity This antibody reacts to MAPK4.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name MAPK4 / ERK4 (MAPK4 Antibody Abstract)
Background Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets.Synonyms: Extracellular signal-regulated kinase 4, MAP kinase isoform p63, Mitogen-activated protein kinase 4, p63-MAPK
Gene ID 5596
NCBI Accession NP_002738
UniProt P31152
Pathways MAPK Signaling
Application Notes ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MAPK4 antibody (Mitogen-Activated Protein Kinase 4) (N-Term) (ABIN359555) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MAPK4 a...
Background publications Lerner-Marmarosh, Miralem, Gibbs et al.: "Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6870-5, 2008 (PubMed).

Kant, Schumacher, Singh et al.: "Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 35511-9, 2006 (PubMed).

Seger, Krebs: "The MAPK signaling cascade." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 9, Issue 9, pp. 726-35, 1995 (PubMed).