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MAPK4 antibody (Mitogen-Activated Protein Kinase 4) (C-Term)

Details for Product anti-MAPK4 Antibody No. ABIN359556, Supplier: Login to see New
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Antigen
Synonyms ERK-4, ERK3, Erk4, MAPK 4, PRKM4, p63MAPK, A330097D03Rik, Erk3, Prkm4, p63Mapk, erk4, wu:fi27d11, zgc:55498, ATMPK4, F2N1.1, F2N1_1, MAP kinase 4
Alternatives
Epitope
C-Term
(23), (22), (15), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(67), (16), (4), (1), (1), (1), (1)
Host
Rabbit
(62), (8), (2), (2), (1)
Clonality
Polyclonal
Conjugate
This MAPK4 antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(64), (40), (36), (13), (12), (4), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the C-term of human MAPK4.
Isotype Ig
Specificity This antibody reacts to MAPK4.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name MAPK4 / ERK4 (MAPK4 Antibody Abstract)
Background Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets.Synonyms: Extracellular signal-regulated kinase 4, MAP kinase isoform p63, Mitogen-activated protein kinase 4, p63-MAPK
Gene ID 5596
NCBI Accession NP_002738
UniProt P31152
Pathways MAPK Signaling
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-MAPK4 antibody (Mitogen-Activated Protein Kinase 4) (C-Term) (ABIN359556) Western blot analysis of anti-MAPK4 Antibody (C-term) in Jurkat cell line lysates (35...
Background publications Lerner-Marmarosh, Miralem, Gibbs et al.: "Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6870-5, 2008 (PubMed).

Kant, Schumacher, Singh et al.: "Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 35511-9, 2006 (PubMed).

Seger, Krebs: "The MAPK signaling cascade." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 9, Issue 9, pp. 726-35, 1995 (PubMed).

Catalog No. ABIN359556
$401.50
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