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CSNK1A1 antibody (Casein Kinase 1, alpha 1) (C-Term)

Details for Product anti-CSNK1A1 Antibody No. ABIN359558, Supplier: Log in to see
Antigen
  • 2610208K14Rik
  • 4632404G05Rik
  • 5430427P18Rik
  • anon-WO03040301.93
  • anon-WO03040301.95
  • CG2028
  • CHUNP6894
  • CK-II
  • CK1
  • ck1
  • ck1a
  • CK1a
  • ck1alpha
  • CK1alpha
  • CK I
  • CKI
  • CkIa
  • CKIa
  • CKIALPHA
  • CKI alpha
  • CKIalpha
  • Csnk1a
  • CSNK2A1
  • dmCK1
  • dmckI
  • Dmel\\CG2028
  • EHK
  • EHK1
  • EPPK
  • HLCDGP1
  • K1
  • KER1
  • KRT1A
  • l(1)G0492
  • NEPPK
  • PKA-C
  • PRO2975
  • wu:fb65a02
  • wu:fi30h04
  • wu:fj19c11
  • zgc:92158
Alternatives
anti-Human CSNK1A1 antibody for Immunofluorescence
Epitope
C-Term
40
14
7
7
6
5
5
5
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
126
41
40
10
8
7
6
4
2
1
1
Host
Rabbit
109
19
2
2
2
Clonality
Polyclonal
Conjugate
This CSNK1A1 antibody is un-conjugated
8
8
4
4
4
4
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
114
79
52
19
15
11
7
2
2
2
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CK1a.
Isotype Ig
Specificity This antibody reacts to CK1a.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name Casein Kinase I alpha (CSNK1A1 Antibody Abstract)
Background Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.Synonyms: CK1, CKI-alpha, CSNK1A1
Gene ID 1452, 9606
UniProt P48729
Pathways WNT Signaling, Hedgehog Signaling
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CSNK1A1 antibody (Casein Kinase 1, alpha 1) (C-Term) (ABIN359558) Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CK1a an...
Western Blotting (WB) image for anti-CSNK1A1 antibody (Casein Kinase 1, alpha 1) (C-Term) (ABIN359558) Western blot analysis of anti-CK1a Pab in A375 cell lysate. CK1a (arrow) was detected...
Background publications Liu, Li, Semenov, Han, Baeg, Tan, Zhang, Lin, He: "Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism." in: Cell, Vol. 108, Issue 6, pp. 837-47, 2002

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002

Fish, Cegielska, Getman, Landes, Virshup: "Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14875-83, 1995