PTK6
Reactivity: Human
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, ICC, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
BRK antibody, Sik antibody, Tksk antibody, tks antibody, zgc:153964 antibody, protein tyrosine kinase 6 antibody, PTK6 protein tyrosine kinase 6 antibody, PTK6 protein tyrosine kinase 6b antibody, PTK6 antibody, Ptk6 antibody, ptk6b antibody
Background
PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation.Synonyms: Breast tumor kinase, Tyrosine-protein kinase 6, Tyrosine-protein kinase BRK