STK10-A antibody (C-Term)

Catalog No. ABIN360364

This Rabbit Polyclonal antibody specifically detects STK10-A in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for STK10-A antibody (C-Term) (ABIN360364)

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK10-A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-STK10-A Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to LOK.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human LOK.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for STK10-A

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Alternative Name: STK10 / LOK

Background: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.Synonyms: EC=2.7.11.1, LOK, Lymphocyte-oriented kinase, STK10, Serine/threonine-protein kinase 10

Gene ID: 6793, 9606

UniProt: O94804