STK10-A antibody (C-Term)

Catalog No. ABIN392476

This Rabbit Polyclonal antibody specifically detects STK10-A in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for STK10-A antibody (C-Term) (ABIN392476)

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK10-A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3401

Product Details anti-STK10-A Antibody

Binding Specificity: AA 692-721, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LOK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human LOK.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for STK10-A

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Alternative Name: LOK

Background: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.

Molecular Weight: 112135

Gene ID: 6793

NCBI Accession: NP_005981

UniProt: O94804