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Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term) antibody

Details for Product No. ABIN360555, Supplier: Login to see
Antigen
  • zgc:77519
  • PACSIN2
  • DKFZp459J1025
  • SDPII
  • AI197433
  • sdpii
  • SdpII
Epitope
C-Term
17
7
4
3
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
42
11
7
3
3
2
2
2
1
1
Host
Rabbit
37
5
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
38
22
21
9
9
6
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PACSIN2.
Isotype Ig
Specificity This antibody reacts to PACSIN2.
Purification Pprotein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name PACSIN2 (PACSIN2 Antibody Abstract)
Background PACSIN may play a role in vesicle formation and transport. This protein homo- and hetero-aggregates with other PACSINs. It also binds dynamin 1, synaptojanin, synapsin 1 and the neural Wiskott-Aldrich syndrome protein (N-WASP). The protein exhibits a cvesicle-like cytoplasmic distribution and is ubiquitously expressed. PACSIN is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). The protein contains 1 FCH domain and 1 SH3 domain.Synonyms: Protein kinase C and casein kinase substrate in neurons protein 2
Gene ID 11252, 9606
UniProt Q9UNF0
Research Area Signaling
Pathways
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Immunofluorescence: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term) antibody (ABIN360555) anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term) antibody
 image for anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term) antibody (ABIN360555) anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term) antibody (Image 2)
Background publications Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Wiemann, Weil, Wellenreuther et al.: "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ..." in: Genome research, Vol. 11, Issue 3, pp. 422-35, 2001 (PubMed).