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Heat Shock 27kDa Protein 1 (HSPB1) antibody
| Antigen | Heat Shock 27kDa Protein 1 (HSPB1) |
| Synonyms |
CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.76067, DKFZp586P1322, MKBP, Hs.78846, LOH11CR1K, MGC133245, 27kDa, Hsp27, hsp1, cb153, hsp25, hsp27, zgc:103437, MGC85307, HSPB1, cmt2f, hsp28, hs.76067, M ...
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| Clonality | Monoclonal (2A5) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives ELISA, Western Blotting (WB)
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| Catalog no. | ABIN361069 |
| Quantity | 50ul (1mg/ml) (Variants) |
| Price | 300.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Alternative name | Hsp27 |
| Immunogen | Recombinant Hsp27, Accession / GI number: NP_001531 |
| Isotype | TBD, kappa chain |
| Clone | 2A5 |
| Description | Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). Hsp27 forms a multimeric complex within cells, and its primary chaperone function, like other small Hsps, appears to be the stabilization of denatured or aggregated proteins in a refolding competent state. |
| Synonyms | CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.76067, DKFZp586P1322, MKBP, Hs.78846, LOH11CR1K, MGC133245, 27kDa, Hsp27, hsp1, cb153, hsp25, hsp27, zgc:103437, MGC85307, HSPB1, cmt2f, hsp28, hs.76067, MGC147259 |
Application Details
| Application Notes | Recommended dilution 1:1000 |
| Concentration | 1mg/ml |
| Purification | The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography |
| Buffer | In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide |
| Storage | Store at -20°, Aliquot to avoid repeated freezing and thawing. |
| Research Area | Heat Shock Proteins |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Heat Shock 27kDa Protein 1 (HSPB1)", type "Antibodies"
| Hosts | Rabbit (127), Mouse (72), Chicken (1) |
| Reactivities | Human (188), Rat (Rattus) (28), Mouse (Murine) (22), Dog (Canine) (10), Chicken (6), Cow (Bovine) (6), Monkey (5), Mammalian (4), Cat (Feline) (3), Fish (3), Goat (3), Guinea Pig (3), Hamster (3), Pig (Porcine) (3), Horse (Equine) (2) |
| Applications | Western Blotting (WB) (184), Immunohistochemistry (IHC) (71), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (61), ELISA (42), Immunofluorescence (IF) (38), Immunoprecipitation (IP) (37), Enzyme Immunoassay (EIA) (29), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Immunocytochemistry (ICC) (15), Flow Cytometry (FACS) (13), Dot Blot (Dot) (4), Immunoelectron Microscopy (IEM) (2), ELISA (Detection) (1), Radioimmunoassay (RIA) (1) |
| Conjugates | Biotin (7), FITC (7), DY488 (1), PE (1) |
| Epitopes | pSer82 (13), pSer78 (12), pSer15 (11), p (4), S78 (2), pSer83 (2), Center (1), S15 (1), S82 (1), S83 (1), pS83 (1), pSer78/82 (1), pSer85 (1) |
