»
Antibodies
»
anti-Toll-Like Receptor 7 (TLR7) antibody
Toll-Like Receptor 7 (TLR7) antibody
| Antigen |
|
| Synonyms |
RGD1563357, TLR7A |
| Clonality |
Monoclonal (4F4) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
Western Blotting (WB) (50), Flow Cytometry (FACS) (24), Immunofluorescence (IF) (22), Enzyme Immunoassay (EIA) (18), ELISA (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Dot Blot (Dot) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
|
| Catalog no. |
ABIN361162 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 5 to 7 Business Days |
|
Alternative name
|
TLR7
|
|
Immunogen
|
Recombinant TLR7, Accession / GI number: NP_057646
|
|
Isotype
|
IgG1, kappa chain (Matching secondary antibodies)
|
|
Clone
|
4F4
|
|
Description
|
TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7,8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.
|
|
Application Notes
|
Recommended dilution 1:1000
|
|
Concentration
|
1mg/ml
|
|
Purification
|
The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
|
|
Buffer
|
In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
|
|
Storage
|
Store at -20°, Aliquot to avoid repeated freezing and thawing.
|
|
Research Area
|
Signaling
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Toll-Like Receptor 7 (TLR7)", type "Antibodies"
|
Hosts
|
Rabbit (52), Mouse (15), Chicken (1), Goat (1)
|
|
Reactivities
|
Human (62), Mouse (Murine) (36), Rat (Rattus) (18), Dog (Canine) (2), Chicken (1), Cow (Bovine) (1)
|
|
Applications
|
Western Blotting (WB) (50), Flow Cytometry (FACS) (24), Immunofluorescence (IF) (22), Enzyme Immunoassay (EIA) (18), ELISA (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Dot Blot (Dot) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
|
|
Conjugates
|
Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Epitopes
|
N-Term (2), extracellular domain (2), C-Term (1), internal (1)
|
Alternatives 
