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Retinoic Acid Receptor, -Isotype antibody
| Antigen | Retinoic Acid Receptor, -Isotype |
| Clonality | Monoclonal (336) |
| Host |
Mouse |
| Reactivity |
Human |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN361388 |
| Quantity | 100 µl |
| Price | 345.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Alternative name | Retinoic Acid Receptor, (-Isotype |
| Format | Affinity-purified |
| Isotype | IgG1 (Matching secondary antibodies) |
| Clone | 336 |
| Description | Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRa, ß and () preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). Anti- Retinoic Acid Receptor, (-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~48k RAR-ß isotype. |
| Specificity | Specific for the ~48k RAR-( isotype. |
Application Details
| Application Notes | Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot. |
| Purification | Prepared from mouse ascites by ammonium sulfate precipitation followed by affinity purification on a protein G column. |
| Storage | Store at -20 °C, stable for 1 year |
| Restrictions | For Research Use only |
