Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (C-Term) antibody

Antigen: Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH)

Synonyms: DBM, DBH, T beta h, TBH, TBetaH, DmelCG1543, CG1543, Dbhl1, Tbh, DOPBHY

Epitope: C-Term

Clonality: Polyclonal

Host: Sheep

Reactivity: Human, Mouse (Murine), Primates

Application: Western Blotting (WB)

Catalog no.: ABIN361427

Additional Information

Alternative name: Dopamine ß-Hydroxylase, C-Terminus

Format: Affinity-purified

Description: DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001). Anti-Dopamine ß-Hydroxylase Western blot of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein.

Specificity: Specific for the ~75k DBH protein in Western blots.

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Purification: Prepared from sheep serum by affinity purification using a Sulfo-Link® column matrix to which the peptide immunogen was coupled.

Storage: Store at -20 °C, stable for 1 year

Restrictions: For Research Use only

Images

Western blots of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein.