DBH antibody (N-Term)

Catalog No. ABIN951969

Cited in 2+ publications. The Rabbit Polyclonal anti-DBH antibody (ABIN951969) specifically detects DBH in WB, IF, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for DBH antibody (N-Term) (ABIN951969)

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBH antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-DBH Antibody

Binding Specificity: AA 34-64, N-Term

Specificity: This antibody recognizes Human DBH (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 34-64 amino acids from the N-terminal region of Human DBH.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-DBH antibody (ABIN951969)

Kawashima, Yajima, Tachiya, Kokubun, Ichikawa, Sato: "Parasympathetic neurons in the human submandibular ganglion." in: Tissue & cell, Vol. 70, pp. 101496, (2021) (PubMed).

Kokubun, Sato, Yajima, Ichikawa: "Distribution of postganglionic neurons which contain dopamine β-hydroxylase, tyrosine hydroxylase, neuropeptide Y and vasoactive intestinal polypeptide in the human middle cervical ganglion." in: Tissue & cell, Vol. 58, pp. 42-50, (2019) (PubMed).

Target Details for DBH

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Alternative Name: Dopamine beta-Hydroxylase

Background: The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq].Synonyms: DBH, DBM, DOPO, Dopamine beta-monooxygenase

Molecular Weight: 69065 Da

Gene ID: 1621

NCBI Accession: NP_000778

Pathways: Carbohydrate Homeostasis