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SOD1 antibody

SOD1 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN361646
  • Target See all SOD1 Antibodies
    SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
    Reactivity
    • 171
    • 98
    • 90
    • 39
    • 23
    • 17
    • 15
    • 15
    • 15
    • 13
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 191
    • 26
    • 6
    • 4
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 195
    • 36
    Polyclonal
    Conjugate
    • 100
    • 28
    • 22
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOD1 antibody is un-conjugated
    Application
    • 211
    • 134
    • 113
    • 58
    • 52
    • 46
    • 31
    • 20
    • 18
    • 14
    • 13
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Specificity
    Detects ~23 kDa (human) and ~19 kDa (other species).
    Cross-Reactivity
    Coral, Cow, Dog, Fish, Hamster, Human, Invertebrate, Mollusca, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus laevis
    Purification
    Protein A Purified
    Immunogen
    Synthetic Human Cu/Zn SOD Peptide
    Top Product
    Discover our top product SOD1 Primary Antibody
  • Application Notes
    • WB (1:5000)
    • IHC (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    0.2 μg/ml of ABIN361645 was sufficient for detection of Cu/Zn SOD in 20 μg of HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:AP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.0, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Leung, Wang, Mak, Ng, Leung: "Differential proteomic responses in hepatopancreas and adductor muscles of the green-lipped mussel Perna viridis to stresses induced by cadmium and hydrogen peroxide." in: Aquatic toxicology (Amsterdam, Netherlands), Vol. 105, Issue 1-2, pp. 49-61, (2011) (PubMed).

    Wong, Leung, Djurisić, Leung: "Toxicities of nano zinc oxide to five marine organisms: influences of aggregate size and ion solubility." in: Analytical and bioanalytical chemistry, Vol. 396, Issue 2, pp. 609-18, (2010) (PubMed).

    Ho, Hsu, Yang, Lee, Chien: "Sialic acid reduces acute endotoxemia-induced liver dysfunction in the rat." in: Shock (Augusta, Ga.), Vol. 32, Issue 2, pp. 228-35, (2009) (PubMed).

    Wu, Hsiao, Chien, Lai: "Ischemic conditioning by short periods of reperfusion attenuates renal ischemia/reperfusion induced apoptosis and autophagy in the rat." in: Journal of biomedical science, Vol. 16, pp. 19, (2009) (PubMed).

    Lahaie-Collins, Bournival, Plouffe, Carange, Martinoli: "Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP+-induced oxidative stress." in: Oxidative medicine and cellular longevity, Vol. 1, Issue 1, pp. 54-62, (2009) (PubMed).

  • Target
    SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
    Alternative Name
    SOD1 (SOD1 Products)
    Synonyms
    LOC692639 antibody, ALS antibody, ALS1 antibody, IPOA antibody, SOD antibody, hSod1 antibody, homodimer antibody, CG11793 antibody, Cu antibody, Cu-Zn SOD antibody, Cu/Zn SOD antibody, Cu/Zn sod antibody, Cu/Zn superoxide dismutase antibody, Cu/ZnSOD antibody, CuSOD antibody, CuZn SOD antibody, CuZn-SOD antibody, CuZn-SOD1 antibody, CuZnSOD antibody, Cu[2+]/Zn[2+]SOD antibody, Dmel\\CG11793 antibody, G antibody, Mn SOD antibody, SOD-1 antibody, SOD1 antibody, Sod-1 antibody, Sod1 antibody, To antibody, To-1 antibody, Zn SOD antibody, Zn Sod antibody, Zn-SOD antibody, ZnSod antibody, cSOD antibody, cSod antibody, dSOD1 antibody, l(3)108 antibody, l(3)68Af' antibody, l(3)G antibody, sod antibody, sod1 antibody, CU/ZN-SOD antibody, SODC antibody, DKFZP469M1833 antibody, B430204E11Rik antibody, Cu/Zn-SOD antibody, Ipo-1 antibody, Ipo1 antibody, SOD1L1 antibody, XSODB antibody, als antibody, als1 antibody, ipoa antibody, sod1-a antibody, ZSOD antibody, cuzn antibody, Cu/Zn superoxide dismutase antibody, superoxide dismutase 1 antibody, Superoxide dismutase 1 antibody, superoxide dismutase 1, soluble antibody, superoxide dismutase 1 S homeolog antibody, Superoxide dismutase [Cu-Zn] antibody, superoxide dismutase 1 L homeolog antibody, superoxide dismutase [Cu-Zn]-like antibody, superoxide dismutase [Cu-Zn] antibody, superoxide dismutase Sod1 antibody, SOD antibody, SOD1 antibody, Sod1 antibody, sod1 antibody, sod1.S antibody, sod-1 antibody, sod1.L antibody, LOC101451855 antibody, LOC101115136 antibody
    Background
    Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (7). SOD3 can also be distinguished by its heparin-binding capacity (1).
    Gene ID
    6647
    NCBI Accession
    NP_000445
    UniProt
    P00441
    Pathways
    Sensory Perception of Sound, Transition Metal Ion Homeostasis
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