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Superoxide Dismutase 2, Mitochondrial (SOD2) antibody

Antigen

Superoxide Dismutase 2, Mitochondrial (SOD2)
Synonyms MnSOD, Sod-2, MGC6144, LOC100101896, Sod2, MNSOD, IPO-B, MVCD6, Mn-SOD, MGC128371, cb463, zgc:73051, wu:fj33b01, GB14346, sod2, MGC88869, SOD2, DKFZp459E042, LOC100282741
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Guinea Pig, Mouse (Murine), Cow (Bovine), Dog (Canine), Chicken, Fruit Fly (Drosophila melanogaster), Pig (Porcine), Hamster, Monkey, Rabbit, Sheep (Ovine), Xenopus laevis
Application
Alternatives Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunohistochemistry (IHC)
Catalog no. ABIN361656
Quantity 100myg  (1mg/mL)  (Variants)
Price 339.00 $   Plus shipping costs $35.00
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anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody

Additional Information
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Characteristics Detects a ~25kDa protein corresponding to the molecular mass of Mn superoxide dismutase (SOD) on SDS PAGE immunoblots.
Alternative name Mn SOD
Gene ID NP_058747.1, 24787
Immunogen Rat Mn SOD
Format Liquid
Description Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (7). SOD3 can also be distinguished by its heparin-binding capacity (1).
Synonyms: Manganese SOD, IPO B, Mn SOD, SOD2
Specificity Detects 25kDa protein, corresponding to the molecular mass of Mn superoxide dismutase (SOD) on SDS-PAGE immunoblots. Species cross-reactivity: Human, Rat, Mouse, Bovine, Canine, Chicken, Drosophila, Guinea Pig, Pig, Hamster, Monkey, Rabbit, Sheep, Xenopus.

Application Details
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Application Notes 0.5ug/ml was sufficient for detection of Mn SOD in 20ug of rat brain tissue extract
Concentration 1mg/mL
Buffer PBS pH7, 50% glycerol, 0.09% sodium azide
Storage -20 °C
Storage Shipping Temp Max Blue Ice or 4 °C
Research Area Oxidative Stress
Restrictions For Research Use only

Alternatives
Application Details Images Secondary Antibodies Variants back to top

Alternatives for antigen "Superoxide Dismutase 2, Mitochondrial (SOD2)", type "Antibodies"
Hosts Rabbit (38), Mouse (21), Sheep (3), Goat (2)
Reactivities Human (56), Rat (Rattus) (28), Mouse (Murine) (25), Dog (Canine) (20), Rabbit (20), Pig (Porcine) (19), Cow (Bovine) (18), Sheep (Ovine) (18), Horse (Equine) (15), Chicken (3), Guinea Pig (3), Hamster (3), Monkey (3), Xenopus laevis (3), Gerbil (2), Fruit Fly (Drosophila melanogaster) (1)
Applications Western Blotting (WB) (40), ELISA (24), Flow Cytometry (FACS) (20), Immunoprecipitation (IP) (19), Immunofluorescence (IF) (18), Immunohistochemistry (IHC) (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates FITC (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)