STAT6 antibody (pThr645)

Catalog No. ABIN361971

The Rabbit Polyclonal anti-STAT6 antibody (ABIN361971) specifically detects STAT6 in IHC. The antibody is reactive with Human samples.

Quick Overview for STAT6 antibody (pThr645) (ABIN361971)

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-STAT6 Antibody

Binding Specificity: pThr645

Specificity: The antibody detects endogenous level of STAT6 only when phosphorylated at threonine 645.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around phosphorylation site of pThr645 (P-A-T (p) -I-K) derived from Human STAT6. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry: 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for STAT6

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Alternative Name: STAT6

Background: Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.

Molecular Weight: 110 kDa

NCBI Accession: NP_003144

UniProt: P42226

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response