Stathmin 1 antibody (pSer16)

Catalog No. ABIN362285

The Rabbit Polyclonal anti-Stathmin 1 antibody is suitable to detect Stathmin 1 in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for Stathmin 1 antibody (pSer16) (ABIN362285)

Target: Stathmin 1 (STMN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Stathmin 1 Antibody

Binding Specificity: pSer16

Specificity: The antibody detects endogenous level of Stathmin 1 only when phosphorylated at serine 16.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around phosphorylation site of pSer16 (R-A-S (p) -G-Q) derived from Human Stathmin 1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin 1

Background: Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear

Molecular Weight: 19 kDa

NCBI Accession: NP_001138

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics