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MEK1 + MEK2 antibody (AA 215-219, AA 219-223)

The Rabbit Polyclonal anti-MEK1 + MEK2 antibody (ABIN362847) specifically detects MEK1 + MEK2 in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.
Catalog No. ABIN362847
$240.90
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Shipping to: United States
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Quick Overview for MEK1 + MEK2 antibody (AA 215-219, AA 219-223) (ABIN362847)

Target

MEK1 + MEK2

Reactivity

  • 31
  • 23
  • 23
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This MEK1 + MEK2 antibody is un-conjugated

Application

  • 23
  • 14
  • 10
  • 5
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Binding Specificity

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    • 1
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    AA 215-219, AA 219-223

    Specificity

    The antibody detects endogenous level of total MEK1/MEK2 protein.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

    Immunogen

    Peptide sequence around AA 215-219, 219-223 (I-D-S-M-A) derived from Human MEK1, MEK2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    Isotype

    IgG
  • Application Notes

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target

    MEK1 + MEK2

    Alternative Name

    MEK1/MEK2

    Background

    Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

    Molecular Weight

    45 kDa

    NCBI Accession

    NP_109587, NP_002746

    UniProt

    Q02750
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