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SMAD3 antibody (AA 423-427)

This Rabbit Polyclonal antibody specifically detects SMAD3 in IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Catalog No. ABIN363050

$350.90

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Quick Overview for SMAD3 antibody (AA 423-427) (ABIN363050)

Target

See all SMAD3 Antibodies

SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Reactivity

Human, Mouse, Rat

Host

Rabbit

Clonality

Polyclonal

Conjugate

This SMAD3 antibody is un-conjugated

Application

Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product SMAD3 Primary Antibody

Binding Specificity
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1

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1
AA 423-427

Specificity

The antibody detects endogenous level of total Smad3 protein.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogen

Peptide sequence around AA 423-427 (C-S-S-V-S) derived from Human Smad3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype

IgG
anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 120-221) antibody
SMAD3 Reactivity: Human WB, ELISA, IHC (p), PLA Host: Mouse Monoclonal 7F3 unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (pSer423), (pSer425) antibody
SMAD3 Reactivity: Human WB, IHC, ELISA, FACS Host: Rabbit Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 120-221) antibody
SMAD3 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2C12 unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 1-110) antibody
SMAD3 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1C11 unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 120-221) antibody
SMAD3 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2C12 unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 1-230) antibody
SMAD3 Reactivity: Human WB, IHC, ELISA, IF, IP Host: Rabbit Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) antibody
SMAD3 Reactivity: Human, Mouse, Rat WB, FACS, IHC (p), IF (cc) Host: Rabbit Monoclonal 3D1 unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 231-425) antibody
SMAD3 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (C-Term) antibody
SMAD3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 3 (SMAD3) (AA 186-215) antibody
SMAD3 Reactivity: Human, Mouse WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB24758 unconjugated

Application Notes

Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target

SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Alternative Name

Smad3

Background

Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Molecular Weight

52 kDa

NCBI Accession

NP_001138

UniProt

P84022

Pathways

Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy