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Details for Product No. ABIN371542

CD16 (GRM1) antibody (Biotin)

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Synonyms CD16, Fcgr3, Fcgr3a, FCGR3, FCGR3@
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Biotin
»Alternatives Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN371542
Quantity 100 tests
275.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Clone GRM1
Isotype IgG2a
Characteristics Synonyms: CD16a, CD16b, FCG3, FCGR3, IGFR3, FCGR3B, Fc-gamma RIII, FcRIII, Low affinityimmunoglobulin gamma Fc region receptor III
Alternative Name CD16
Background CD16 (FcgammaRIII) serves as a low affinity IgG receptor. Human CD16 is expressed in twoforms CD16a and CD16b. CD16a is a transmembrane protein of monocytes, macrophages,NK cells and a subset of T cells. CD16b is a GPI-linked monomeric receptor expressed onneutrophils and is involved in their activation and induction of a proadhesive phenotype. CD16 is involved in NK activation and signal transduction. (Ref. 1-5)
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: 10 µL/10e6 cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.09% Sodium Azide as preservative.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Ravetch, Perussia: "Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions." in: The Journal of experimental medicine, Vol. 170, Issue 2, pp. 481-97, 1989 (PubMed).

Takai, Li, Sylvestre et al.: "FcR gamma chain deletion results in pleiotrophic effector cell defects." in: Cell, Vol. 76, Issue 3, pp. 519-29, 1994 (PubMed).

Alternatives for antigen "CD16 (GRM1)", type "Antibodies"
Hosts (200), (15), (1)
Reactivities (194), (25), (12), (11), (5), (1)
Applications (181), (68), (31), (28), (21), (17), (10), (6), (5), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Conjugates (30), (27), (24), (6), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Epitopes (2), (1), (1)