TAAR1 antibody (AA 225-250)

Catalog No. ABIN372246

Product Details anti-TAAR1 Antibody

Target: TAAR1 (Trace Amine Associated Receptor 1 (TAAR1))

Binding Specificity: AA 225-250

Reactivity: Human, Rat, Monkey, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAAR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes Trace Amine Associated Receptor 1 (TAAR1/TA1).

Cross-Reactivity (Details): Species reactivity (expected):Chimpanzee, Monkey and Rat.
Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogen: Synthetic peptide corresponding to the amino acids 225-250 of human TAAR1.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.05 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for TAAR1

Target: TAAR1 (Trace Amine Associated Receptor 1 (TAAR1))

Alternative Name: TAAR1 (TAAR1 Products)

Synonyms: RP11-295F4.9 antibody, TA1 antibody, TAR1 antibody, TRAR1 antibody, Tar1 antibody, Trar1 antibody, taR-1 antibody, si:dkey-7c18.14 antibody, trace amine associated receptor 1 antibody, trace amine-associated receptor 1 antibody, trace-amine-associated receptor 1 antibody, trace amine associated receptor 1b antibody, TAAR1 antibody, Taar1 antibody, taar1b antibody

Background: TA1 (Trace amine receptor 1) is a member of the G protein coupled receptor family (subfamily trace amine). It is activated by endogenous trace amines as well as metabolites of the biogenic amine neurotransmitters. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. This receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach. An EST for TA1 has been identified from a human stomach cancer library.Synonyms: TA1, TAR1, TRAR1, TaR-1, Trace amine receptor 1, Trace amine-associated receptor 1

Gene ID: 134864

NCBI Accession: NP_612200

UniProt: Q96RJ0