AMPD1 antibody (AA 500-550)

Catalog No. ABIN372278

Product Details anti-AMPD1 Antibody

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Binding Specificity: AA 500-550

Reactivity: Human, Mouse, Rat, Cow, Monkey, Chimpanzee, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMPD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes AMPD1.

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Chimpanzee, Monkey, Mouse, Rat and Zebrafish.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 500-550 of Human AMPD1.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 5-10 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for AMPD1

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Alternative Name: AMP Deaminase 1 / AMPD1 (AMPD1 Products)

Synonyms: ampd1 antibody, MAD antibody, MADA antibody, AI553520 antibody, Ampd-1 antibody, Ampd01 antibody, RATAMPD01 antibody, zgc:77905 antibody, adenosine monophosphate deaminase 1 antibody, N-acetyl-anhydromuranmyl-L-alanine amidase antibody, N-acetylmuramoyl-L-alanine amidase antibody, Negative regulator of beta-lactamase expression antibody, adenosine monophosphate deaminase 1 (isoform M) antibody, AMPD1 antibody, ampD1 antibody, ampd1 antibody, Ampd1 antibody

Background: AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.Synonyms: AMP deaminase isoform M, Myoadenylate deaminase

Molecular Weight: 87 kDa.

Gene ID: 270

NCBI Accession: NP_000027

UniProt: P23109