SLC40A1 antibody (N-Term)

Catalog No. ABIN372307

Product Details anti-SLC40A1 Antibody

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC40A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes MTP1/SLC40A1 (N-term).

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated corresponding to N-terminal residues of Human MTP1 (Metal Transporter Protein 1).

Isotype: IgG

Application Details

Application Notes: Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SLC40A1

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Alternative Name: MTP1 (SLC40A1 Products)

Synonyms: FPN1 antibody, HFE4 antibody, IREG1 antibody, MST079 antibody, MTP1 antibody, SLC11A3 antibody, slc39a1 antibody, weh antibody, slc40a1 antibody, MGC82700 antibody, SLC40A1 antibody, Fpn1 antibody, Slc11a3 antibody, Slc39a1 antibody, Dusg antibody, MTP antibody, Ol5 antibody, Pcm antibody, ARABIDOPSIS THALIANA IRON-REGULATED PROTEIN 1 antibody, ATIREG1 antibody, FERROPORTIN 1 antibody, T19C21.5 antibody, T19C21_5 antibody, iron regulated 1 antibody, ARABIDOPSIS IRON-REGULATED TRANSPORTER 1 antibody, ATIRT1 antibody, T16H5.50 antibody, T16H5_50 antibody, iron-regulated transporter 1 antibody, solute carrier family 40 member 1 antibody, solute carrier family 40 (iron-regulated transporter), member 1 antibody, solute carrier family 40 (iron-regulated transporter), member 1 S homeolog antibody, iron regulated 1 antibody, iron-regulated transporter 1 antibody, SLC40A1 antibody, slc40a1 antibody, slc40a1.S antibody, Slc40a1 antibody, IREG1 antibody, IRT1 antibody

Background: SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.Synonyms: Ferroportin-1, Fpn1, Ireg1, Iron-regulated transporter 1, Metal transporter protein 1, Slc11a3, Slc39a1, Slc40a1, Solute carrier family 40 member 1

Molecular Weight: 63 kDa

Gene ID: 30061

NCBI Accession: NP_055400

UniProt: Q9NP59

Pathways: Transition Metal Ion Homeostasis