ALAS1 antibody (AA 480-530)

Catalog No. ABIN372400

Product Details anti-ALAS1 Antibody

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Binding Specificity: AA 480-530

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALAS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes ALAS1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of amino acids 480-530 of human ALAS1.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ALAS1

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Alternative Name: ALAS1 (ALAS1 Products)

Synonyms: ALAS antibody, ALAS3 antibody, ALASH antibody, MIG4 antibody, ALAS-N antibody, Alas-1 antibody, Alas-h antibody, ALAS-H antibody, ALASN antibody, ALAS1 antibody, wu:fb58d01 antibody, wu:fi12g09 antibody, 5'-aminolevulinate synthase 1 antibody, aminolevulinic acid synthase 1 antibody, alanyl-tRNA synthetase protein antibody, aminolevulinate, delta-, synthase 1 antibody, ALAS1 antibody, Alas1 antibody, alas1 antibody, alas1.S antibody, alaS1 antibody

Background: Delta Aminolevulinate Synthase catalyzes the condensation of glycine with succinyl CoA to form delta aminolevulinic acid. This nuclear encoded mitochondrial enzyme is the first and rate limiting enzyme in the mammalian heme biosynthetic pathway.Synonyms: 5-aminolevulinate synthase nonspecific mitochondrial, 5-aminolevulinic acid synthase, ALAS3, ALASH, Delta-ALA synthetase, Delta-aminolevulinate synthase

Molecular Weight: 71 kDa.

Gene ID: 211

NCBI Accession: NP_000679

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha