SMC4 antibody (AA 281-297)

Catalog No. ABIN372444

The Rabbit Polyclonal anti-SMC4 antibody (ABIN372444) specifically detects SMC4 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SMC4 antibody (AA 281-297) (ABIN372444)

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SMC4 Antibody

Binding Specificity: AA 281-297

Specificity: This antibody recognizes Structural Maintenance Of Chromosomes 4 (SMC4).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogen: Synthetic peptide corresponding to Amino acids 281-297 of human CAPC.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SMC4

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Alternative Name: SMC4 / CAPC

Background: The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.Synonyms: Chromosome-associated polypeptide C, SMC4L1, Structural maintenance of chromosomes protein 4, XCAP-C homolog, hCAP-C

Gene ID: 10051

NCBI Accession: NP_001002800

UniProt: Q9NTJ3