SMC4 antibody (N-Term)

Catalog No. ABIN6972758

Product Details anti-SMC4 Antibody

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Characteristics: The Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into condensed mitotic chromosomes. SMC4 forms a heterodimer with SMC2 and contains a myosin-like ATPase domain that serves as a molecular motor to help organize chromatin. During mitosis, most of the condensin complex is associated with the chromatin. SMC4 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This SMC4 antibody was raised against a peptide from the N-terminus of human SMC4.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for SMC4

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Alternative Name: SMC4 (SMC4 Products)

Synonyms: CAP-C antibody, CAPC antibody, SMC-4 antibody, SMC4L1 antibody, hCAP-C antibody, 2500002A22Rik antibody, C79747 antibody, Smc4l1 antibody, cb788 antibody, chunp6901 antibody, fb99b10 antibody, smc4l1 antibody, wu:fb99b10 antibody, xcap-c antibody, ARABIDOPSIS THALIANA CHROMOSOME ASSOCIATED PROTEIN-C antibody, ARABIDOPSIS THALIANA STRUCTURAL MAINTENANCE OF CHROMOSOME 4 antibody, ATCAP-C antibody, ATSMC3 antibody, ATSMC4 antibody, K15N18.7 antibody, K15N18_7 antibody, STRUCTURAL MAINTENANCE OF CHROMOSOMES 3 antibody, structural maintenance of chromosome 3 antibody, Structural maintenance of chromosomes protein 4 antibody, structural maintenance of chromosomes 4 antibody, structural maintenance of chromosomes 4 L homeolog antibody, structural maintenance of chromosome 3 antibody, smc-4 antibody, SMC4 antibody, Smc4 antibody, smc4 antibody, smc4.L antibody, SMC3 antibody

Molecular Weight: 175 kDa

NCBI Accession: NP_001002800