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Myotubularin 1 (MTM1) (C-Term) antibody

Details for Product No. ABIN374119
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Antigen
Synonyms wu:fb19c01, zgc:123266, CNM, MTMX, XLMTM, AF073996, Mtm, mKIAA4176
Epitope
C-Term
(12), (6), (4), (4), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human
(49), (29), (18), (12), (12)
Host
Goat
(41), (5), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(40), (23), (10), (7), (7), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN374119
357.50 $
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Immunogen eptide with sequence C-SSPSQMMPHVQTHF, from the C Terminus of the protein sequence Genename: MTM1
Specificity This antibody detects MTM1 at C-term. Species Reactivity: Tested: Human. Expected from sequence similarity: Bovine.
Purification Affinity chromatography
Alternative Name Myotubularin / MTM1
Background Dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. Could be involved in a signal transduction pathway necessary for late myogenesis, although its ubiquitous expression suggests a wider function.
Gene ID 4534
NCBI Accession NP_000243.1
UniProt Q13496
Application Notes Peptide ELISA: 1/16000. Western blot: 0.3 - 1 µg/ml. Approx 70kDa band observed in lysates of Human SkeletalMuscle and of cell line HepG2 (calculated MW of 69.9kDa according to NP_000243.1). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Myotubularin 1 (MTM1) (C-Term) antibody anti-Myotubularin 1 (MTM1) (C-Term) antibody
anti-Myotubularin 1 (MTM1) (C-Term) antibody (2) anti-Myotubularin 1 (MTM1) (C-Term) antibody (Image 2)
Background publications Laporte, Hu, Kretz et al.: "A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast." in: Nature genetics, Vol. 13, Issue 2, pp. 175-82, 1996 (PubMed).

Validation Images
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