IRF2 antibody (C-Term)

Catalog No. ABIN374254

This Goat Polyclonal antibody specifically detects IRF2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog and Cow.

Quick Overview for IRF2 antibody (C-Term) (ABIN374254)

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This IRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRF2 Antibody

Binding Specificity: C-Term

Sequence: TSDITQARVK SC

Specificity: This antibody detects IRF2 at C-term.

Cross-Reactivity (Details): Species reactivity (expected):Rat, Dog, Cow.
Species reactivity (tested):Human, MOuse.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_002190.2. Genename: IRF2

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 2000. Western blot: 1-3 μg/mL. Approx 45-50 kDa band seen in Jurkat lysate (Expected MW fromamino acid sequence according to NP_002190.1 is 40 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Target Details for IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Alternative Name: IRF2

Background: IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. However, IRF2 also functions as a transcriptional activator of histone H4.Synonyms: IRF-2, Interferon regulatory factor 2

Gene ID: 3660

NCBI Accession: NP_002190

UniProt: P14316