FOXN1 antibody (C-Term)

Catalog No. ABIN374354

The Goat Polyclonal anti-FOXN1 antibody is suitable to detect FOXN1 in samples from Human. It has been validated for IHC (p).

Quick Overview for FOXN1 antibody (C-Term) (ABIN374354)

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This FOXN1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FOXN1 Antibody

Binding Specificity: C-Term

Sequence: C-SVYLSPSSKP VALA

Specificity: This antibody detects FOXN1 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_003584.2. Genename: FOXN1

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 32000. Immunohistochemistry: 20-30 μg/mL. In paraffin embedded Human Thymus Medullashows speculate nuclear staining in some of the Medullar cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Target Details for FOXN1

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Alternative Name: FOXN1

Background: The FOXN1 gene encodes a DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, nail dystrophy, and the skin disorder congenital alopecia.Synonyms: Forkhead box protein N1, RONU, WHN, Winged-helix transcription factor nude

Gene ID: 8456

NCBI Accession: NP_003584

UniProt: O15353