HPGD antibody (C-Term)

Catalog No. ABIN374495

Product Details anti-HPGD Antibody

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This HPGD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Prostaglandin dehydrogenase 1.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-DYDTTPFQAKTQ, from the C Terminus of the protein sequence

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HPGD

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Alternative Name: HPGD (HPGD Products)

Synonyms: CBR antibody, SDR21C1 antibody, hCBR1 antibody, 15-PGDH antibody, PGDH antibody, PGDH1 antibody, PHOAR1 antibody, SDR36C1 antibody, MGC80546 antibody, MGC79454 antibody, AV026552 antibody, carbonyl reductase 1 antibody, 15-hydroxyprostaglandin dehydrogenase antibody, hydroxyprostaglandin dehydrogenase 15-(NAD) antibody, 15-hydroxyprostaglandin dehydrogenase L homeolog antibody, hydroxyprostaglandin dehydrogenase 15 (NAD) antibody, CBR1 antibody, HPGD antibody, hpgd.L antibody, hpgd antibody, pgdh antibody, Hpgd antibody, PTRG_03214 antibody, VDBG_09957 antibody

Background: Prostaglandins are involved in many physiologic and cellular processes, such as inflammation. The NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) is the main enzyme of prostaglandin degradation. By catalyzing the conversion of the 15-hydroxyl group of prostaglandins into a keto group, this ubiquitous enzyme strongly reduces the biologic activity of these molecules. The induction of 15-PGDH expression by dexamethasone and other glucocorticoids at the therapeutic level provides an additional biochemical mechanism for the anti-inflammatory action of these glucocorticoids.Synonyms: 15-hydroxyprostaglandin dehydrogenase, PGDH, PGDH1, Prostaglandin dehydrogenase 1

Gene ID: 3248

NCBI Accession: NP_000851

UniProt: P15428